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    (±)-C75

    更新:2017-9-15 10:30:27

      中文名:(±)-C75
      英文名:tetrahydro-4-methylene-2R-octyl-5-oxo-3S-furancarboxylic acid
      別名:
      CAS No.:191282-48-1級別:
      分子式:C14H22O4分子量:254.3
    訂購信息
      貨號規格價格品牌
      10005270-10mg10mg2950GBCBIO
      10005270-10mg10mg3550Cayman
    產品介紹
      Inhibition of fatty acid synthase (FAS) by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines.1 (±)-C75 is a stable inhibitor of FAS that leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.2 (±)-C75 is also cytotoxic to many human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway
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